Sodium trifluoroacetate is a trifluoromethylating agent for compounds like aromatic halides, aldehydes and ketones.
应用:
Sodium trifluoroacetate can be used:
As a trifluoromethylating agent in nucleophilic trifluoromethylation of aldehydes using copper(I) halide catalyst.
As a difluorocarbene precursor in gem-difluorocyclopropanation of different alkenes using azobisisobutyronitrile (AIBN) as a catalyst.
In the synthesis of trifluoromethylthio-substituted aromatic compounds via copper-mediated oxidative trifluoromethylthiolation of aryl boronic acids in the presence of elemental sulfur.
